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Anyway...had at it a bit myself. Started with flipping the case, and then...well, have a look:
There's definitely some changes. The Quad VCO is paired with the Quad VCA, for starters. This lets you do a lot of CVable mixing of the VCOs, creating morphing-like structures, or really most anything. Mangroves next, then a CVable wavefolder, which not only lets you morph the formants, but also the timbral quality of the Mangroves. Two attenuators to control their levels going into the Sisters VCF...and this is key, because I looked at that filter and noted that it has this extra input, CENTRE, that allows a 'lead' part to get 3db out front and be timbrally altered against the other sounds coming in via the ALL, LO, or HI inputs. The dual attenuator lets you have more control over that lead/back balance.
Then there's a Doepfer A-106-1 filter. This is actually a filter pair, based on the Korg MS-20's Sallen-Key pair, but with the sick and twisted addition of an insert in its resonance path. Hence the stuff below: a Chronoblob delay and a VERB digital reverb. Now, what came to my diseased mind was this: put the Chronoblob into the A-106-1's insert. Now, the Chronoblob ALSO has an insert...this time, in the feedback path. So the CVable VERB goes into THAT...allowing clocked delay pulsations with the added strangeness of constantly-shifting 'room' depths, with all of this being constantly inline to alter the dual filter's behavior. Tres ambient! Of course, there's plenty of other ways to (ab)use those, too...
ER-301 is above the other set of VCAs, next to a little 4-in stereo mixer, which is next to the Clouds. This puts the Clouds in place to easily process/mangle incoming audio OR the synth's sounds themselves, and all of this can be sent up and thru the ER-301 for more processing mayhem. The I/O is right below in the tile row, also, so the right end of the build can do a lot of 'spiderwebbing' amongst all of these for pretty infinite possibilities of subpatching for sonic alteration.
Bottom (now) tile row. Added the uMIDI 1U because the Intellijel cab's USB port (on the backplane) directly links to that for MIDI-over-USB use. Above this are your Monome modules, and this puts all incoming control signals at the lower left...nice and cohesive. Modulation/clocking is next to this, with the corresponding tile below the Tides and MATHS so everything's all in place to work as a modulation subpatch team. The row went to the bottom, also, to get your external cable runs below and away from your patchwork to avoid confusion. It also puts the tile controls close at hand to your controller for fast 'nuance' adjustment.
Sole flaw here is that I wound up being forced to drop the multiple. However, you might find that using stackable cables and/or inline mult modules work even better in this small a rig.
Downside of all of this: $5,668, modules alone. Definitely above the $2500 line, but it gives you something of a point to aim for, money-wise, even if the module compliment might change. But this isn't a bad aiming point, IMHO...definitely feels like an ambient 'instrument'.
Whatcha think?