If you want to be perfect, make sure that your tuning note is an "a". But this is already academic, there is no real reason, as long as it is only your oscillator that must be in tune to your samples.
-- Durst
um, usually the lowest note of a sequencer, that uses actual notes, is a 'c' so tuning to a 'c' makes more sense - or to an interval from a 'c; - so that every note is an interval from 'c' alternately substitute a different root note for the c - and then the sequencer plays intervals to that root note
this also works with most quantizers as they don't care about root note... and if they do they're usually sending notes relative to 'c' (0v is usually c0)
"some of the best base-level info to remember can be found in Jim's sigfile" @Lugia
Utility modules are the dull polish that makes the shiny modules actually shine!!!
sound sources < sound modifiers < modulation sources < utilities