Thanks for the feedback, I've been looking at Frames as I'm going through a MI phase at the moment but i'm still researching this area.

I'm currently using a BeatStep Pro & Korq SQ1 for sequencing which I'm pretty happy with, however, I'd love to get my hands on a Rene!

Also, I'm sending all the audio into a studio firewire mixer - straight into my DAW which works well for me :-)