The ES compatibility list shows the 2i4 as being suitable, and since the preamp topology is the same across that series, the 8i6 should be fine. However, I wouldn't use the SPDIF I/O. Instead, see if your DAW can recognize both interfaces, with the 828 on FW400 and the 8i6 via USB. Most present-day DAWs should be able to cope.
-- Lugia

Unfortunately, on Ableton/Windows I think it can only see one interface. I was using the Focusrite just for MIDI for a while but whenever I turn on the Focusrite, it takes control of my audio like a beotch. Interestingly, my TR-8S shows up as audio interface option as well...

JB