Hey! Personally I lean toward going for the smaller case and limiting your options. I did an experiment in January where I scaled down to 100 hp with a Benjolin, a dual filter, some envelopes, S&Hs,VCAs, and attenuators, a mini Clouds clone and a micro Ornament and Crime and had an amazing time exploring all the different sounds I could get out of just that. I was also choosing to record it direct (with a little looping and reverb at times), but if you want to record into a DAW or sampler you could do a ton with a smaller case. I strongly support limiting your options and forcing yourself to get creative to arrive at sounds you like. If you think you want to have whole compositions with multiple voices running simultaneously, it would certainly be easier with the larger case. Follow your bliss friend!